Testosterone enanthate Features

Chemical structure

Testosterone Enanthate – androgen, testosterone dissolved in the oil with the attached through 17-beta hydroxy group enantatnym ether (17b-hydroxy-androst-4-ene-3-one). Its half-life in the body is about 6-8 days (the full life of 15-16 days), the chemical formula C7H14O2. Esterified steroids such polar not as free steroids, they are not absorbed so rapidly from the injection site. Proceeding in the circulatory system, the ether is cleaved, further blood travels free testosterone. Esterified steroids were developed in order to prolong the therapeutic effect after the injection, and in order to be able to inject less when compared to the free steroid injections. The concentration of 200mg of testosterone enanthate introduced increases of 4 days, and then uniformly reduced to the 5-th day after injection. It turns out that in order to maintain a high concentration of drug in the blood, it is necessary to carry out an injection every 5th day (seven-day dose or split into 2 parts). Making calculation of dosages, one should not forget that 100 mg of testosterone enanthate contains much less principal hormone than 100 mg sodium testosterone (suspension) (in this case, the amount of hormone is 72 mg, the remaining 28 mg is necessary for mass enantatnogo ether) .

Historical reference

Testosterone enanthate for the first time began to sell in the international market in the early 1950s. It is the first oil-based steroid which action was sustained. Later it became widely practiced. The most famous product, which includes the drug – Testoviron from Schering, marketed for 50 years. Testosterone enanthate is used in a clinical setting for the treatment of men who have low levels of androgens, it is manifested in the reduction of potency, loss of energy and the like. Testosterone enanthate is used as a drug controlling the birth rate. As a result of the research it was reported that weekly injections of 200 mg in 7 days for three months significantly reduced sperm production. Regardless of what is now an increasing number of alternative treatments, testosterone enanthate continues to be one of the most popular drugs in the market.

Mode of action (according to the manufacturer)

At testosterone enanthate specific androgenic effect: it has a stimulating effect on the development and function of the external genitalia, prostate, seminal vesicles, including secondary sexual characteristics in males (voice, hair growth). Take part in the formation of the constitution of the body and sexual behavior in men, stimulates the libido and potency, it has stimulated spermatogenesis. It reduces the production of follicle stimulating hormone and lyuteotropnogo. Testosterone is an antagonist of female sex hormones – estrogen, it priststvuet antitumor effect in breast tumors in women. Has anabolic effect is manifested in the stimulation of protein synthesis, decrease fat deposits, delay in the body necessary for the synthesis of protein, potassium, phosphorus, sulfur, strengthening the fixation of calcium in the bones and increasing muscle mass. In that case, if the athlete receives a sufficient amount of protein nutrition, it stimulates the production of erythropoietin. In adolescent boys and drug used in the treatment of growth at therapeutic doses.

The steroid testosterone enanthate profile

  1. Active substance: 15-16 days
  2. Classification: steroid anabolic / androgenic origin
  3. Method of application: injection
  4. Dosage: Men 250mg – 1000mg / Women do not advise
  5. Acne: Yes
  6. Water Retention: high
  7. High blood pressure: excess doses
  8. Hepatotoxicity: no
  9. Aromatase: High
  10. DHT (dihydrotestosterone) conversion: yes
  11. Decrease HPTA function (producing its own testosterone): yes (it provokes a decrease in the size of the testicles after PKT their size is reduced)
  12. Anabolic activity (100%) \ androgenic activity (100%)
  13. The detection time – 4 months (about in connection with that DC is improved in finding methods for detection of prohibited substances, it also depends on the athlete, whether it accepts phenobarbital and furosemide to accelerate withdrawal of drug)

The effects of testosterone enanthate

  • It provides a noticeable weight gain
  • Does the rapid increase in the force
  • Good effect on the joints (due to accumulation of water)
  • It has a good effect Pumping
  • It affects the stimulation of regenerative processes in the body
  • It improves the desire to train, as well as the overall vitality

Application of testosterone enanthate

Reception (for men):

For athletes recommended dosage of 250-500 (750-1000) mg / week course from 4 to 8 (12) weeks. These doses is enough for maximum muscle growth and strength parameters. You should also not forget that it is necessary to apply the anti-estrogens on the course.

Reception (for women):

Due to the high androgenic activity of this drug to women are not advised to use

Side effects of testosterone enanthate

Estrogen excess, as a consequence of exposure enanthate, may lead to the development of gynecomastia, including androgenic side effects. This can be intensive work of the sebaceous glands, acne, hair growth on the body and face, male-pattern baldness (hereditary, it is possible to stop the process, taking finasteride, but a side effect of this drug is to decrease libido) in order to minimize the development of side effects are advised to take Proviron (Mesterolone), anastrozole or exemestane. After the course of PCT (with a view to restoring a high level of endogenous testosterone, without him after the course there will be a significant decline).

Among side effects may occur as follows: precocious puberty, cancer, and abnormalities of the prostate gland, increased erections and increased sexual arousal, reducing the volume of ejaculate, oligospermia, premature closure of growth zones bones, depression, headache, anxiety, paresthesia, insomnia, nausea, bleeding in the gastrointestinal tract, cholestatic jaundice, other androgenic effects (including hirsutism, and seborrhea).

Indications for use of testosterone enanthate drug

Testosteronzamestitelnaya therapy in men with pathological conditions that are associated with primary and secondary hypogonadism, both congenital and acquired, restoring libido after urogenital operations.

Contraindications to the use of testosterone enanthate drug

Known or suspected prostate cancer or breast cancer, hypersensitivity to any component of the drug, children up to 3 years (due to the fact that the preparation contains benzyl alcohol), the boys in the prepubertal period, in order to avoid premature closure of the epiphysis and precocious puberty; chronic heart failure, kidney and / or liver failure in order to prevent the development of edema; diabetes; prostatic hypertrophy with symptoms of urinary retention; sleep apnea, as well as risk factors such as obesity and chronic lung disease; childhood.

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